What to do When You Have a Migraine and Stomach Pain


Migraine is a common headache disorder affecting more than 12% of people worldwide with many signs and symptoms. These include pain, sensitivity to light and sound, and even sweating. 

However, migraine has also been associated with some rather unusual symptoms. These symptoms are not usually associated with headaches, such as stomach pain. This pain can result from a proposed connection between the stomach and the gut. Other cases abound where the stomach pain with the migraine may result from a co-occurring condition. In any case, this article will thoroughly discuss this medical condition, as well as the necessary steps you can take to treat such discomfort. 

Stomach Pain as a Symptom of Migraine

Results from various studies indicate that there is a close link between migraine and incidences of gastrointestinal (GI) conditions. A 2021 research has further noted that nausea and vomiting are common in people suffering from migraines. The condition’s exact cause is not quite established, but the link between the brain and the gut has been termed the “gut-brain connection” or the “gut-brain axis.”

This connection suggests that a person suffering from migraines may also experience stomach aches, as research has corroborated. Possible reasons for this connection include the following:

  • The Immune system mediators: Some elements of your immune system control inflammation. These components may also be responsible for migraine and stomach pain. 
  • Calcitonin gene-related peptide (CGRP): Additionally, the release of CGRP in your body can instigate migraine pain and aggravate the acids in the stomach. 
  • Neurotransmitters: Some microbes in the gut may affect the activity of glutamate and serotonin. As a result, these elements within your body may cause gut pain and migraine. 
  • Stress hormones: Finally, hormones like cortisol can change the balance of microbes within the gut and cause headache pain.

How to Treat Migraine and Stomach Pain 

Various prescribed medications may help reduce the symptoms of such a medical condition. These include: 

  • Metoclopramide;
  • Chlorpromazine;
  • Prochlorperazine.

Furthermore, a 2020 research highlighted that dietary changes could reduce stomach symptoms and migraines. These include the following: 

  • Eating enough fiber;
  • Limiting your sugar intake;
  • Ensuring that supplements are part of your dietary meal. Supplements include omega-3, vitamin D etc; and
  • Staying hydrated at all times. 


Conclusively, over-the-counter medications for treating migraines may have side effects. Therefore, you must manage such side effects by consulting your doctor to know which drug will better treat your migraine.