Unwind Naturally: 7 Dietitian-Approved Vitamins and Supplements to Combat Stress

Stress is a constant part of our lives, and sometimes, it leads to fatigue, upset stomach, and irritability. However, several vitamins and supplements can help you handle stress better. This article covers 7 vitamins and supplements to help you deal with stress.

HUM Nutrition Big Chill (Best With Rhodiola Rosea)

Rhodiola is a natural, nontoxic herb that stimulates your body’s stress response system to boost stress resistance. According to a small 8-week study involving 100 people with chronic fatigue symptoms, such as short-term memory and concentration impairments, supplementing with 400 mg of Rhodiola extract per day improved symptoms after a week.

Innate Vitality Magnesium Glycinate (Best With Magnesium)

Magnesium involves multiple healthy bodily functions, such as blood sugar and blood pressure regulation. According to one older study in 100 people discovered that people who supplemented with 400 mg of magnesium daily for 90 days had increased heart rate variability (HRV) compared to a control group.

Life Extension Melatonin IR/XR (Best With Melatonin)

Melatonin regulates your body’s circadian rhythm. Levels of this hormone increase in the evening when it’s dark to promote sleep and reduce in the morning to boost wakefulness.

Some research also suggests that supplementing with melatonin might help because stress is connected to insomnia.

Pure Encapsulations L-Theanine (Best with L-theanine)

L-theanine is known for its ability to decrease stress and boost relaxation without having sedative effects. A high-quality study of 30 people discovered that taking 200 mg of L-theanine daily significantly improved depression symptoms and sleep quality.

In another study, in 34 people, drinking a beverage consisting of 200 mg of L-theanine and other nutrients reduced cortisol levels in response to a stressful task that involved multitasking.

Klaire Labs Ashwagandha Extract (Best With Ashwagandha)

In one study on the stress-relieving effects of ashwagandha, it was connected to a more significant reduction in stress and depression.

Nordic Naturals Vitamin D3 1000 (Best With Vitamin D)

One of Vitamin D’s primary functions is to help your body absorb more calcium. However, researchers have discovered it could reduce inflammation and promote immune function. This vitamin could also help reduce stress in people with vitamin D deficiency.

MegaFood Balanced B Complex (Best With B-complex Vitamins)

B vitamins are essential for heart and brain health. Some researchers also suggest that high doses of B vitamins could improve stress symptoms, such as mood and energy levels.


Multiple vitamins and supplements have been connected to reduced stress symptoms, such as Rhodiola rosea, melatonin, ashwagandha, and vitamin D. However, consult your doctor before trying a new supplement, especially if you’re pregnant or taking other medications.

If nothing changes in your stress levels, speak to a medical professional or therapist about possible solutions.